Tuesday, February 5, 2013

CB Receptor Agonists - IRONWOOD PHARMACEUTICALS, INC

CB Receptor Agonists - IRONWOOD PHARMACEUTICALS, INC

"Cannabinoid receptors (CB) agonists may be used for treating immune disorders, liver fibrosis, inflammation and disorders that have an inflammatory component, such as cardiovascular disease, osteoporosis and renal ischemia. In addition, CB agonists may also be used in the treatment of emesis and pain including acute, chronic, inflammatory, post-operative, cancer and neuropathic pain.
Thus, there is a need to develop compounds useful as selective agonists of the cannabinoid receptors.

SUMMARY

The compounds disclosed herein, and pharmaceutically acceptable compositions thereof, are effective as CB agonists. These compounds have the general formula I:
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